Synthesis p. 520 - 526 (2010)
Update date:2022-09-26
Topics: 1,2-Diamines Benzimidazoles Imidazolines
Murai, Kenichi
Takaichi, Nobuhiro
Takahara, Yusuke
Fukushima, Shunsuke
Fujioka, Hiromichi
A novel method for the preparation of imidazolines and benzimidazoles bearing an amide at the 2-position, is described. The reactions of the glyoxamide with aliphatic and aromatic 1,2-diamines were found to form five-membered imidazolines and benzimidazoles by a one-pot condensation-oxidation procedure.
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