Total synthesis of Hirtellanine A

DOI: 10.1016/j.tetlet.2010.03.092

Source and publish data:

Tetrahedron Letters p. 2883 - 2887 (2010)

Update date:2022-07-29

Topics:

Authors:

Zheng, Shu-Yan

Shen, Zheng-Wu

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Article abstract of DOI:10.1016/j.tetlet.2010.03.092

The first total synthesis of hirtellanines A is described. The key transformations include (i) base-mediated regioselective pyran ring formation, (ii) one-pot sequential boronation and Suzuki-Miyaura cross-coupling, and (iii) a tandem acid-induced deprotection and subsequent tautomerizations.

Full text of DOI:10.1016/j.tetlet.2010.03.092

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