Journal of the American Chemical Society p. 7890 - 7892 (2010)
Update date:2022-08-02
Topics:
Poisson, Thomas
Yamashita, Yasuhiro
Kobayashi, Shu
Catalytic asymmetric protonation of chiral calcium enolates was performed. Chiral calcium enolates, prepared in situ from imides and malonates via 1,4-addition in the presence of catalytic amounts of Ca(OEt)2, Ph-PyBox, and achiral phenol, were smoothly protonated to afford adducts bearing tertiary asymmetric carbons in high yields with high enantioselectivities. The adducts were readily converted to optically active 2-substituted 1,5-dicarboxylic acid derivatives.
View MoreTianjin Crest Pharmaceutical R&D Co., Ltd. （Tianjin Yao Technology Development Co., Ltd.）(expird)
Contact:+86-22-66211386
Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457
website:https://www.yacoo.com.cn/en/
Contact:86-512-87182055
Address:No.112 Xinqing Rd, Suzhou Industrial Park, China, 215125, China
Shuanghe Bio-Technology Limited(expird)
Contact:+86-571-61710758,18968016640
Address:Jinqiao north road 916# Fuyang
Jiande City Silibase Silicone New Material Manufacture Co., Ltd.
Contact:15967177856
Address:Genglou Industrial Development Area
Tianjin SPHINX SCIENTIFIC LAB.
Contact:+86-022-66211289
Address:Tianda high-tech Park. No.80,the 4th Avenue
Doi:10.1016/j.bmc.2019.115069
(2019)Doi:10.1016/0040-4020(89)80011-0
(1989)Doi:10.1016/j.tet.2010.03.055
(2010)Doi:10.1021/ja00202a066
(1989)Doi:10.1021/cc100054u
(2010)Doi:10.1039/P19890001067
(1989)
