
Journal of Medicinal Chemistry p. 543 - 552 (1990)
Update date:2022-08-04
Topics:
LaMattina, John L.
McCarthy, Peter A.
Reiter, Lawrence A.
Holt, William F.
Yeh, Li-An
A series of 4-substituted 2-guanidinothiazoles has been found to inhibit the gastric proton-pump enzyme H+,K+-ATPase.In general, these compounds were reversible inhibitors of canine gastric H+,K+-ATPase, competi
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