HIGHLY STEREOSELECTIVE FREE RADICAL C-6-ALLYLATION OF PENAMS-SYNTHESIS OF A NOVEL Β-LACTAMASE INHIBITOR

DOI: 10.1016/0040-4020(89)80006-7

Source and publish data:

Tetrahedron p. 941 - 950 (1989)

Update date:2022-08-04

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Authors:

Hanessian, Stephen

Alpegiani, Marco

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Article abstract of DOI:10.1016/0040-4020(89)80006-7

Highly efficient radical-induced C-allylation is possible with 6-bromo and 6,6-dibromopenams with excellent chemo- and stereoselectivity. 6-β-Allyl penicillin 1,1-dioxide sodium salt is a novel β-lactamase inhibitor.

Full text of DOI:10.1016/0040-4020(89)80006-7

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