Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging

DOI: 10.1002/cmdc.201000013

Source and publish data:

ChemMedChem p. 777 - 789 (2010)

Update date:2022-08-05

Topics:

Authors:

Breyholz, Hans-Joerg

Wagner, Stefan

Faust, Andreas

Riemann, Burkhard

Hoeltke, Carsten

Hermann, Sven

Schober, Otmar

Schaefers, Michael

Kopka, Klaus

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Article abstract of DOI:10.1002/cmdc.201000013

Matrix metalloproteinases (MMPs) are zinc- and calcium-dependent endopeptidases. Representing a subfamily of the metzincin superfamily, MMPs are involved in the proteolytic degradation of components of the extracellular matrix. Unregulated MMP expression,

Full text of DOI:10.1002/cmdc.201000013

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