European Journal of Medicinal Chemistry p. 141 - 148 (1992)
Update date:2022-08-05
Topics:
Faraj
Maillard
Lemaitre
Letellier
Frappier
Florent
Grierson
Monneret
Zerial
Based on the known structure-activity relationships for the active anti-HIV, a series of 3'-deoxy-3'-N-functionalized thymidine analogs has been synthesized from thymidine. Evaluation for inhibitory activity against human immunodeficiency virus (HIV) replication in CEM cells and against herpes simplex virus in MRC-5 cells is reported.
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