Compatibility of thioamides with reverse turn features: Synthesis and conformational analysis of two model cyclic pseudopeptides containing thioamides as backbone modifications

DOI: 10.1021/ja00157a064

Source and publish data:

Journal of the American Chemical Society p. 433 - 441 (1990)

Update date:2022-09-26

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Authors:

Sherman Sherman

Spatola Spatola

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Article abstract of DOI:10.1021/ja00157a064

The incorporation of thioamides within the backbone of linear peptides can produce subtle physical changes but have profound effects on biological activities and selectivity. To study the compatibility of thioamides with reverse turns (1←3 and 1]4 hydroge

Full text of DOI:10.1021/ja00157a064

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