(METHYL DIFLUOROACETATE)COPPER REAGENT. REMARKABLE SOLVENT EFFECT ON THE 19F-NMR SPECTRUM, STABILITY AND REACTIVITY

DOI: 10.1246/cl.1989.389

Source and publish data:

Chemistry Letters p. 389 - 392 (1989)

Update date:2022-07-30

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Authors:

Kitagawa, Osamu

Taguchi, Takeo

Kobayashi, Yoshiro

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Article abstract of DOI:10.1246/cl.1989.389

The 19F-NMR spectrum, thermal stability and reactivity of (methyl difluoroacetate)copper reagent were found to differ remarkably depending on the solvent (DMSO, DMF, or HMPA) used.With allylic bromide or alkynyl halide a crucial solvent effect for the coupling reactions was observed.

Full text of DOI:10.1246/cl.1989.389

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