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7447-41-8

Basic Information
CAS No.: 7447-41-8
Name: Lithium chloride
Molecular Structure:
Molecular Structure of 7447-41-8 (Lithium chloride)
Formula: ClLi
Molecular Weight: 42.39
Synonyms: Lithiumchloride (6CI,8CI);Lithium monochloride;NSC327172;
EINECS: 231-212-3
Density: 2.608 g/cm3
Melting Point: 605 °C(lit.)
Boiling Point: 1382 °C
Flash Point: -4°F
Solubility: 832 g/L (20 °C) in wtaer
Appearance: White powder
Hazard Symbols: FlammableF, HarmfulXn, CorrosiveC, IrritantXi
Risk Codes: 11-36/38-22-36/37/38-35-10-36/37-19-63-20/21/22
Safety: 26-37/39-36/37/39-16-36-45-33-29-22
Transport Information: UN 2789 8/PG 2
PSA: 0.00000
LogP: -2.99600
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  • Lithium chloride (LiCl)

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  • Lithium chloride

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Consensus Reports

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Specification

The Lithium chloride is an organic compound with the formula LiCl. The IUPAC name of this chemical is lithium chloride. With the CAS registry number 7447-41-8, it is also named as hydrochloric acid lithium salt. The product's categories are Inorganics; Lithium Compounds; Classes of Metal Compounds; Li (Lithium) Compounds; Typical Metal Compounds; ACS GradeSynthetic Reagents; Essential Chemicals; BioUltraProtein Structural Analysis; DNA&RNA Purification; Molecular Biology; Molecular Biology Reagents; Optimization ReagentsMolecular Biology; Reagents; X-Ray Crystallography; Crystal Grade Inorganics; Lithium Salts; LithiumMetal and Ceramic Science; Metal and Ceramic Science; Salts; Inorganic Salts; Lithium; Synthetic Reagents; Cell Separation (Centrifugation) MediaEssential Chemicals; Hematology and Histology; Reagent Plus; Routine Reagents; LithiumMolecular Biology; Plant Nucleic Acid Purification; ReagentsPlant Molecular Biology; Optimization Reagents; Analytical Reagents for General Use; E-L, Puriss p.a. ACS; Puriss p.a. ACS. Besides, it is a colorless crystals or powder, which should be stored in a cool, dry place. 

Preparation: this chemical can be prepared by Hydrochloric acid and Hydrochloric acid. Chemical reaction is as follows:

Uses of Lithium chloride: it is mainly used for the production of lithium metal by electrolysis of a LiCl/KCl melt at 600 °C. LiCl is also used as a brazing flux for aluminium in automobile parts. Also, in biochemical applications, it can be used to precipitate RNA from cellular extracts. Lithium chloride is also used as a flame colorant to produce dark red flames. It is used as a desiccant for drying air streams. In more specialized applications, lithium chloride finds some use in organic synthesis.

When you are using this chemical, please be cautious about it as the following:
It is highly flammable, harmful by inhalation, in contact with skin and if swallowed and may form explosive peroxides. Besides, this chemical is irritating to eyes, respiratory system and skin and can cause severe burns. It is danger of cumulative effects and May cause cancer. When you are using it, wear suitable gloves and eye/face protection, keep away from sources of ignition - No smoking, do not breathe dust and empty into drains, take precautionary measures against static discharges. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: [Li+].[Cl-]
(2)InChI: InChI=1/ClH.Li/h1H;/q;+1/p-1
(3)InChIKey: KWGKDLIKAYFUFQ-REWHXWOFAB
(4)Std. InChI: InChI=1S/ClH.Li/h1H;/q;+1/p-1
(5)Std. InChIKey: KWGKDLIKAYFUFQ-UHFFFAOYSA-M

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 422mg/kg (422mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat LD50 intraperitoneal 492mg/kg (492mg/kg)   Russian Pharmacology and Toxicology Vol. 42, Pg. 9, 1979.
cat LDLo subcutaneous 450mg/kg (450mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
dog LDLo intravenous 500mg/kg (500mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

MUSCULOSKELETAL: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 100, Pg. 429, 1950.
frog LDLo subcutaneous 885mg/kg (885mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
guinea pig LD50 intraperitoneal 624mg/kg (624mg/kg)   "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 157, 1999.
guinea pig LDLo subcutaneous 620mg/kg (620mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
human LDLo oral 200mg/kg/3D (200mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: MUSCLE WEAKNESS
JAMA, Journal of the American Medical Association. Vol. 139, Pg. 688, 1949.
human TDLo oral 243mg/kg/13D (243mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR

GASTROINTESTINAL: NAUSEA OR VOMITING
JAMA, Journal of the American Medical Association. Vol. 139, Pg. 688, 1949.
mouse LD50 intracrebral 14040ug/kg (14.04mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 75, 1973.
mouse LD50 intraperitoneal 600mg/kg (600mg/kg)   Journal of Thermal Biology. Vol. 6, Pg. 87, 1981.
mouse LD50 intravenous 363mg/kg (363mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: ANTIPSYCHOTIC
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 413, 1973.
mouse LD50 oral 1165mg/kg (1165mg/kg)   Russian Pharmacology and Toxicology Vol. 33, Pg. 266, 1970.
mouse LD50 subcutaneous 738mg/kg (738mg/kg) BEHAVIORAL: TREMOR

MUSCULOSKELETAL: OTHER CHANGES
Acta Pharmacologica et Toxicologica. Vol. 43, Pg. 51, 1978.
pigeon LDLo subcutaneous 513mg/kg (513mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
quail LD50 oral 422mg/kg (422mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
rabbit LD50 oral 800mg/kg (800mg/kg)   Farmakologiya i Toksikologiya Vol. 39, Pg. 53, 1976.
rabbit LDLo subcutaneous 531mg/kg (531mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LD50 intracrebral 4800ug/kg (4.8mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Polish Journal of Pharmacology and Pharmacy. Vol. 26, Pg. 399, 1974.
rat LD50 intraperitoneal 514mg/kg (514mg/kg)   Personal Communication from K.P. Petersen, DAK Labs., 59 Lergravsvej, DK-2300, Copenhagen, Demark, Dec. 22, 1977Vol. 22DEC1977,
rat LD50 intratracheal 205mg/kg (205mg/kg)   "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 157, 1999.
rat LD50 oral 526mg/kg (526mg/kg)   Acta Pharmacologica et Toxicologica. Vol. 47, Pg. 351, 1980.
rat LD50 subcutaneous 499mg/kg (499mg/kg)   Personal Communication from K.P. Petersen, DAK Labs., 59 Lergravsvej, DK-2300, Copenhagen, Demark, Dec. 22, 1977Vol. 22DEC1977,