Use of Radical Ring-Opening for Introduction of Alkyl and Substituted Alkyl Groups with Stereochemical Control: A Synthetic Application of Cyclopropylcarbinyl Radicals

Article abstract of DOI:10.1021/jo00012a009

Cyclopropylcarbinols 2a and 2b (see Scheme I), which are accessible by a number of routes, can be converted into the corresponding radicals 3a and 3b, respectively.These radicals undergo peripheral ring-opening of the cyclopropyl substructure to afford su