A chemoselective deoxygenation of N-oxides by sodium borohydride-Raney nickel in water

DOI: 10.1016/j.tetlet.2010.08.045

Source and publish data:

Tetrahedron Letters p. 5690 - 5693 (2010)

Update date:2022-08-05

Topics:

Authors:

Gowda, Narendra B.

Rao, Gopal Krishna

Ramakrishna, Ramesha A.

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Article abstract of DOI:10.1016/j.tetlet.2010.08.045

A simple and convenient protocol for deoxygenation of aliphatic and aromatic N-oxides to the corresponding amines in good to excellent yield using sodium borohydride-Raney nickel in water is reported. Other functional moieties such as alkenes, halides, ethers, and amides are unaffected under the present reaction condition.

Full text of DOI:10.1016/j.tetlet.2010.08.045

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