NUCLEOSIDE PHOSPHONODITHIOATES AS INTERMEDIATES IN THE PREPARATION OF DINUCLEOSIDE PHOSPHORODITHIOATES AND PHOSPHOROTHIOATES

Article abstract of DOI:10.1016/S0040-4039(01)80782-6

5'-O-(9-Phenylxanthen-9-yl)thymidine (1) is converted into the triethylammonium salt of its 3'-phosphonodithioate (2a) in good yield; the latter compound is converted into a dinucleoside phosphonothioate (4a) and thence into a dinucleoside phosphorodithio