Stereoselective synthesis of analogs of the macrolactone of isomigrastatin

DOI: 10.1016/j.tetlet.2011.12.020

Source and publish data:

Tetrahedron Letters p. 707 - 709 (2012)

Update date:2022-08-03

Topics:

Authors:

Dias, Luiz C.

Monteiro, Gustavo C.

Amarante, Giovanni W.

Conegero, Leila S.

Finelli, Fernanda G.

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Article abstract of DOI:10.1016/j.tetlet.2011.12.020

An approach for the highly stereoselective synthesis of analogs of the macrolactone of isomigrastatin is described. Our optimized strategy is based on a very efficient lactone opening, a Wittig olefination reaction and a ring closing metathesis. The synth

Full text of DOI:10.1016/j.tetlet.2011.12.020

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