Enhanced Cyclization of N-Benzyloxycarbonyl-N-substituted Dipeptide Methyl Esters with Ammonia

DOI: 10.1246/bcsj.62.2404

Source and publish data:

Bulletin of the Chemical Society of Japan p. 2404 - 2406 (1989)

Update date:2022-07-30

Topics: Cyclization Methyl ester Dipeptide N-Substituted Methyl esters Ammonia

Authors:

Kawashiro, Katsuhiro

Nishiguchi, Kazuhisa

Kurosaka, Ikuo

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Article abstract of DOI:10.1246/bcsj.62.2404

Cyclization of N,N'- dimethyl ester to the hydantoin derivative took place easily under mild ammonolysis conditions.Replacement of Z by p-methoxy-benzyloxycarbonyl also led to the cyclizatio

Full text of DOI:10.1246/bcsj.62.2404

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