SYNTHESIS OF N,O-PROTECTED DERIVATIVES OF 2'-O-METHYLCYTIDINE AND OF 2'-O-METHYL- AND N1-METHYLGUANOSINES

Article abstract of DOI:10.1007/BF00597663

Using selective 3',5'-O-tetraisopropyldisiloxane protection, N-acyl-2'-O-methyl derivatives of cytidine and guanosine and of 2'-O-tetrahydropyranyl-N₁-methyl-guanosine have been synthesized.It has been shown that the spatial screening of the am