Stereoselective Reduction of α-Cyclopropyl Ketones and α-Cyclopropyl Aldols. Stereo-directing Effect by α-Trimethylsilyl Group

DOI: 10.1016/S0040-4039(01)80590-6

Source and publish data:

Tetrahedron Letters p. 5447 - 5450 (1989)

Update date:2022-07-31

Topics: -Reduction

Authors:

Shimazaki, Masato

Hara, Hisaaki

Suzuki, Keisuke

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)80590-6

Stereoselective reduction of α-chiral α-cyclopropyl ketones and α-cyclopropyl aldols is described.Introduction of trimethylsilyl (TMS) group to the α-position of cyclopropyls leads to virtually complete stereoselection to give the stereo-defined β-cyclopr

Full text of DOI:10.1016/S0040-4039(01)80590-6

Products guided by the article

Product name:(3R,4R)-3-Methyl-2-trimethylsilanyl-dodec-1-en-4-ol

Cas No:127583-01-1

R&D Labs maybe for 127583-01-1

HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China
Beijing Mediking Biopharm Co., Ltd.

Contact:+86-10-89753524/81760121/81769521

Address:Hongxianghong Incubator, Beiqijia Town, Changping district, Beijing, China
SHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.

website:http://www.tychemical.com

Contact:0086-358-3521713 3521715

Address:No. 1 Yintong Road, Shanxi Jiaocheng Economic Development Zone, Xiajiaying Town, Jiaocheng County, Lvliang City, Shanxi Province, China
Changzhou Kingyo Chemical Corporation Ltd.

website:http://www.kingyochem.com

Contact:+86-519-85105717

Address:19# Wuqing North Road, Changzhou , Jiangsu, China

Relevant to this article

Doi:10.1021/ja01343a057
(1932)
(Naphthalen-1-yloxy)-acetic acid benzylidene/(1-phenylethylidene)-hydrazide derivatives: Synthesis, antimicrobial evaluation, and QSAR studies

Doi:10.1007/s00044-011-9776-0
(2012)
Beta-adrenergic blocking agents. IV. Variation of the 2-naphthyl group of pronethalol (2-isopropylamino-1-(2-naphthyl)ethanol).

Doi:10.1021/jm00303a027
(1969)
Self-Assembly of Disorazole C₁ through a One-Pot Alkyne Metathesis Homodimerization Strategy

Doi:10.1002/anie.201501922
(2015)
STERIC EFFECTS OF PHOSPHINE LIGANDS ON THE PHOTOCHEMISTRY PF Mn2(CO)10

Doi:10.1016/0022-328X(83)80199-5
(1983)
Spectroscopic and TD-DFT studies on the turn-off fluorescent chemosensor based on anthraldehyde N(4) cyclohexyl thiosemicarbazone for the selective recognition of fluoride and copper ions

Doi:10.1016/j.poly.2016.01.021
(2016)

Article Doi