SYNTHETIC STUDIES TOWARDS (-)-CARBA-3'-DEOXY-3'-FLUOROTHYMIDINE

DOI: 10.1016/S0040-4020(01)85137-1

Source and publish data:

Tetrahedron p. 6271 - 6280 (1989)

Update date:2022-08-05

Topics:

Authors:

Beres, J.

Sagi, Gy.

Baitz-Gacs, E.

Toemoeskoezi, I.

Gruber, L.

Oetvoes, L.

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Article abstract of DOI:10.1016/S0040-4020(01)85137-1

Stereospecific synthesis of (-)-carba-3'-deoxy-3'-fluorothymidine (-)-11 is reported from the protected (-)-carbocyclic 3'-epi-thymidine (-)-7 using diethylaminosulfur trifluoride.Under the conditions used, extensive dehydration of the blocked precursor i

Full text of DOI:10.1016/S0040-4020(01)85137-1

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