Tricyclic Heteroaromatic Systems. Benzopyranopyrrol-4-ones and Benzopyrano-1,2,3-triazol-4-ones as Benzodiazepine Receptor Ligands. Synthesis and Structure-Activity Relationships

Article abstract of DOI:10.1021/jm00171a047

The synthesis, ability to displace <3H>flunitrazepam binding from bovine brain membranes, and GABA ratio of some <1>benzopyranopyrroles 1a-i and <1>benzopyrano-1,2,3-triazoles 2a,b are reported.The GABA ratios of some previously synthesized pyrazoloquinol