Antiandrogenic steroidal sulfonylpyrazoles

DOI: 10.1021/jm00170a008

Source and publish data:

Journal of Medicinal Chemistry p. 2094 - 2100 (1990)

Update date:2022-08-04

Topics:

Authors:

Christiansen

Bell Bell

D'Ambra D'Ambra

Mallamo Mallamo

Herrmann

Ackerman

Opalka Opalka

Kullnig Kullnig

Winneker

Snyder Snyder

Batzold Batzold

Schane Schane

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00170a008

The steroidal sulfonylpyrazole 1 bound to the rat ventral prostate androgen receptor in vitro; it inhibited testosterone propionate induced increases in ventral prostate weight in vivo in the castrated, immature male rat with an ED₅₀ of 15 mg/k

Full text of DOI:10.1021/jm00170a008

Products guided by the article

Product name:(1R,3aS,3bR,5aS,10aS,10bS,12aS)-1-Ethynyl-7-methanesulfonyl-10a,12a-dimethyl-1,2,3,3a,3b,4,5,5a,6,7,10,10a,10b,11,12,12a-hexadecahydro-7,8-diaza-dicyclopenta[a,h]phenanthren-1-ol

Cas No:127881-88-3

R&D Labs maybe for 127881-88-3

CHINA MEHECO CORPORATION

Contact:+86-10-67147360/67107388

Address:No.18 Guangming Zhongjie, Chongwen District, Beijing, 100061, China
Pengchen New Material Technology Co., Ltd.

Contact:+86-512-63680537

Address:99.6 km of national road 318, Meiyan Community,Pingwang Town, Wujiang District, Suzhou 215225
Shanghai Surseechem Co.,Ltd.

Contact:+86-21-61318535

Address:Building 29,No.2139 Xizha Road, Fengxian District, Shanghai
shandong zhongke taidou chemical co.,ltd

Contact:86-531-88682301

Address:Jinan shandong Province CHina
Qingdao Kylin Trading Co., Ltd.

Contact:0086-532-68979884/58972912/68972263/65/88171519

Address:Room 2308,A building International Trade Center No.230 Changjiang Middle Road of Qingdao Economic Development Zone,Shandong,China.

Relevant to this article

STRUCTURE OF FR 900483, A NEW IMMUNOMODULATOR ISOLATED FROM A FUNGUS

Doi:10.1016/S0040-4039(00)82028-6
(1988)
Di(methylimidazole)prolinol silyl ether catalyzed highly Michael addition of aldehydes to nitroolefins in water

Doi:10.1021/ol901204b
(2009)
Iridium-catalyzed isomerization of primary allylic alcohols under mild reaction conditions

Doi:10.1016/j.tetlet.2009.04.130
(2009)
Diverting β-Hydride Elimination of a ?-Allyl Pd^IICarbene Complex for the Assembly of Disubstituted Indolines via a Highly Diastereoselective (4 + 1)-Cycloaddition

Doi:10.1021/acs.orglett.0c02374
(2020)
Stereoselective synthesis of N-heterocycles: application of the asymmetric Cu-catalyzed addition of Et₂Zn to functionalized alkyl and aryl imines

Doi:10.1016/j.tet.2009.04.002
(2009)
Total synthesis and absolute configuration of the natural amino acid tetrahydrolathyrine

Doi:10.1021/jo900800x
(2009)

Article Doi