Antiandrogenic steroidal sulfonylpyrazoles

DOI: 10.1021/jm00170a008

Source and publish data:

Journal of Medicinal Chemistry p. 2094 - 2100 (1990)

Update date:2022-08-04

Topics:

Authors:

Christiansen

Bell Bell

D'Ambra D'Ambra

Mallamo Mallamo

Herrmann

Ackerman

Opalka Opalka

Kullnig Kullnig

Winneker

Snyder Snyder

Batzold Batzold

Schane Schane

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Article abstract of DOI:10.1021/jm00170a008

The steroidal sulfonylpyrazole 1 bound to the rat ventral prostate androgen receptor in vitro; it inhibited testosterone propionate induced increases in ventral prostate weight in vivo in the castrated, immature male rat with an ED₅₀ of 15 mg/k

Full text of DOI:10.1021/jm00170a008

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