Regioselective Reductive Ring Cleavage of 3-Benzyltetrahydro-1,3-oxazines to 3-Dialkylaminopropanols and of 3-Benzyl-3-methyltetrahydro-1,3-oxazinium Iodides to Alkyl 3-Dialkylaminopropyl Ethers

DOI: 10.1055/s-1990-26819

Source and publish data:

Synthesis p. 153 - 156 (1990)

Update date:2022-07-29

Topics:

Authors:

Alberola, Angel

Alvarez, M. Angeles

Andres, Celia

Gonzalez, Alfonso

Pedrosa, Rafael

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Article abstract of DOI:10.1055/s-1990-26819

3-Benzyltetrahydro-1,3-oxazines and their methiodides are ring-cleaved upon reduction with lithium aluminum hydride to give 3-dialkylaminopropanols or alkyl 3-dialkylaminopropyl ethers, respectively, in good yields.The reducing agent regioselectively clea

Full text of DOI:10.1055/s-1990-26819

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