Regioselective Reductive Ring Cleavage of 3-Benzyltetrahydro-1,3-oxazines to 3-Dialkylaminopropanols and of 3-Benzyl-3-methyltetrahydro-1,3-oxazinium Iodides to Alkyl 3-Dialkylaminopropyl Ethers

DOI: 10.1055/s-1990-26819

Source and publish data:

Synthesis p. 153 - 156 (1990)

Update date:2022-07-29

Topics:

Authors:

Alberola, Angel

Alvarez, M. Angeles

Andres, Celia

Gonzalez, Alfonso

Pedrosa, Rafael

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1990-26819

3-Benzyltetrahydro-1,3-oxazines and their methiodides are ring-cleaved upon reduction with lithium aluminum hydride to give 3-dialkylaminopropanols or alkyl 3-dialkylaminopropyl ethers, respectively, in good yields.The reducing agent regioselectively clea

Full text of DOI:10.1055/s-1990-26819

Products guided by the article

Product name:3-Benzyl-2-(4-methoxy-phenyl)-[1,3]oxazinane

Cas No:128017-05-0

R&D Labs maybe for 128017-05-0

Changzhou Foreign Trade Corp

Contact:+86-519-86623222

Address:29F/D, 99 Yanling West Road, Changzhou, Jiangsu, China
QUZHOU ZIO I/E CO.;LTD

Contact:13357117572

Address:No.149 Shiji dadao Road.
Tangshan Wisdom Trading Co.,Ltd

Contact:86 315 2222979

Address:No.41 BeiXinXi Road, Yangguang building 1-1102 , Tangshan, Hebei, China
Wuxi Pharma-Trading Import & Export Co.,Ltd.

Contact:+86-510-82304590 82716390

Address:Room 523,Youzu Alliance Building,No.88 Renmin Zhonglu,Wuxi,Jiangsu,China
ENERGYCO LTD.

Contact:+86-25-83719363

Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China

Relevant to this article

Synthesis of new hyodeoxycholic acid thiosemicarbazone derivatives under solvent-free conditions using microwave

Doi:10.1016/j.cclet.2010.10.020
(2011)
Preparation of optically active apoverbenone and verbenone from nopinone by use of the sulfenylation-dehydrosulfenylation method. Stability and reactivity attributable to absolute configuration at the sulfur atom in sulfoxides

Doi:10.1021/jo9807316
(1998)
Iron-Catalyzed C(sp²)-C(sp³) Cross-Coupling of Chlorobenzenesulfonamides with Alkyl Grignard Reagents: Entry to Alkylated Aromatics

Doi:10.1021/acs.joc.8b02886
(2019)
Regiochemistry in cobalt-mediated intermolecular Pauson-Khand reactions of unsymmetrical internal heteroaromatic alkynes with norbornene

Doi:10.1021/jo200664m
(2011)
Facile one-pot access to a chiral at metal ruthenium pyrrolyl phosphine phosphoramidite complex

Doi:10.1016/j.inoche.2011.01.004
(2011)
Constituents of Osmanthus absolute, 1st communication: 2,5-epoxy-megastigma-6,8-dienes

Doi:10.1002/hlca.19780610134
(1978)

Article Doi