Michael addition of methyl 2-(trimethysily)propenoate with organomagnesiums or organolithiums leading to 1:1 and / or 2:1 adducts and subsequent peterson olefination by condensation with carbonyl compounds

DOI: 10.1246/bcsj.63.466

Source and publish data:

Bulletin of the Chemical Society of Japan p. 466 - 475 (1990)

Update date:2022-08-03

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Authors:

Tanaka Tanaka

Kanemasa

Ninomiya

Tsuge Tsuge

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Article abstract of DOI:10.1246/bcsj.63.466

Michael addition of methyl 2-(trimethylsilyl)propenoate with organomagnesiums or organolithiums leads to 1:1 and/or 1:2 adduct anions which can be utilized in the subsequent step of Peterson olefination with carbonyl compounds. The 1:1/1:2 ratio depends u

Full text of DOI:10.1246/bcsj.63.466

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Product name:7-ethyl 1-methyl 2-benzylidene-4-methoxycarbonyl-4,6-bis(trimethylsilyl)heptanedioate

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