Journal of Fluorine Chemistry p. 385 - 391 (1990)
Update date:2022-08-05
Topics:
Toulgui, Ch.
Chaabouni, M. M.
Baklouti, A.
β-Fluoroamine compounds were obtained from 2-fluorotosylates by action of an excess of amines in dimethyl sulfoxide.The substitution of the tosyl group by amine takes place in all the studied cases whereas the elimination of toluene-p-sulphonic acid (HOTs) is not observed.This process is a good general method for the synthesis of primary, secondary and tertiary β-fluoroamines in acceptable yields.
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