Tetrahedron Letters p. 7261 - 7264 (1989)
Update date:2022-09-26
Topics: Synthesis Mannosidase inhibitors Swainsonine 1,4-dideoxy-1,4-imino-D-mannitol Ring contracted swainsonines (1S, 2R, 7R, 7aR)-1,2,7-trihydroxypyrrolizidine (1S, 2R, 7S, 7aR)-1,2,7-trihydroxypyrrolizidine
Carpenter, Neil M.
Fleet, George W. J.
Bello, Isabelle Cenci di
Winchester, Bryan
Fellows, Linda E.
Nash, Robert J.
4,5-Anhydro-1-azido-1-deoxy-2,3-O-isopropylidene-D-talitol is a divergent intermediate for the efficient and practical syntheses of 1,4-dideoxy-1,4-imino-D-mannitol, swainsonine and of the ring contracted swainsonines, (1S, 2R, 7R, 7aR)-1,2,7-trihydroxypyrrolizidine and (1S, 2R, 7S, 7aR)-1,2,7-trihydroxypyrrolizidine.The effect on glycosidases of the ring contracted swainsonines is reported.
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Doi:10.1111/febs.13351
(2015)Doi:10.1021/ml5001933
(2014)Doi:10.1055/s-0030-1259066
(2010)Doi:10.1039/c5ra06935a
(2015)Doi:10.1016/0022-328X(90)85374-8
(1990)Doi:10.1016/S0040-4020(01)81775-0
(1991)