Inhibition of Human Leukocyte Elastase. 2. Inhibition by Substituted Cephalosporin Esters and Amides

DOI: 10.1021/jm00171a029

Source and publish data:

Journal of Medicinal Chemistry p. 2522 - 2528 (1990)

Update date:2022-08-03

Topics:

Authors:

Finke, Paul E.

Ashe, Bonnie M.

Knight, Wilson B.

Maycock, Alan L.

Navia, Manuel A.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00171a029

A variety of 7α-methoxycephalosporin ester and amide sulfones were prepared and tested to determine the structure-activity relations for inhibition of human leukocyte elastase (HLE), a serine protease which has been implicated in several degenerative lung

Full text of DOI:10.1021/jm00171a029

Products guided by the article

Product name:N,N'-diisopropyl-O-isourea

Cas No:128472-96-8

R&D Labs maybe for 128472-96-8

Hangzhou Mole's Science & Technology Co.,Ltd.(expird)

Contact:+86-571-56880228

Address:15F Guodu development Building, NO.182 Zhaohui Road
Shanghai Apeptide Co., Ltd.

website:http://www.apeptides.com/en/

Contact:+86-21-60871011

Address:No. 80 Chuanshan Shuyuan Steet,Pudong,Shanghai
jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china
Chengdu Yunyi International Trade Co., Ltd

Contact:

Address:china
MINS GROUP CO.,LIMITED

Contact:18669908765

Address:Zibo City, Shandong Province, P.R.China

Relevant to this article

Isolable p - And m -[(^tBu₂MeSi)₂Si] ₂C₆H₄: Disilaquinodimethane vs triplet bis(silyl radical)

Doi:10.1021/ja2014746
(2011)
Chitosan-Silica Sulfate Nano Hybrid as a Novel and Highly Proficient Heterogeneous Nano Catalyst for Regioselective Ring Opening of Epoxides via Carboxylic Acids

Doi:10.1002/hlca.201700144
(2017)
Reaction of amino sugars with malondialdehyde

Doi:10.1016/0008-6215(90)84188-Z
(1990)
(E)-N ²-{4-[(E)-2-(4-chlorobenzoyl)-ethenyl]-3-methyl-1-phenyl- 1H-pyrazol-5-yl}-N¹,N¹-dimethyl-formamidine: Polarized molecules within sheets of π-stacked hydrogen-bonded chains

Doi:10.1107/S0108270110012023
(2010)
EFFICIENT SYNTHESIS OF (+)-NOJIRIMYCIN AND (+)-1-DEOXYNOJIRIMYCIN

Doi:10.1016/0040-4039(90)80078-Z
(1990)
Doi:10.1021/jo00944a019
(1973)

Article Doi