Synthesis and Dopamine Receptor Affinities of 2-(4-fluoro-3-hydroxyphenyl)ethylamine and N-Substituted Derivatives

DOI: 10.1021/jm00171a014

Source and publish data:

Journal of Medicinal Chemistry p. 2408 - 2412 (1990)

Update date:2022-08-05

Topics: Synthesis N-substituted derivatives Dopamine

Authors:

Claudi, Francesco

Cardellini, Mario

Cingolani, Gian Mario

Piergentili, Alessandro

Pertuzzi, Guidubaldo

Balduini, Walter

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Article abstract of DOI:10.1021/jm00171a014

The synthesis of 2-(4-fluoro-3-hydroxyphenyl)ethylamine (26) and of some N,N-dialkyl derivatives (27-30) starting from 4-fluoro-3-hydroxytoluene and their in vitro binding affinities for dopamine (DA) receptor are reported.The amine 26 can be regarded as

Full text of DOI:10.1021/jm00171a014

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