Tetrahedron p. 2255 - 2262 (1990)
Update date:2022-07-29
Topics:
Firestone
Barker
Pisano
Ashe
Dahlgren
Two types of monocyclic azetidinones have been synthesized that were designed to inactivate human leukocyte elastase (HLE) in three steps: first, acylation of active-site serine; second, creation of a powerful new electrophilic center; third, covalent cap
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(1991)