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56-86-0

Basic Information
CAS No.: 56-86-0
Name: L-Glutamic acid
Molecular Structure:
Molecular Structure of 56-86-0 (L-Glutamic acid)
Formula: C5H9NO4
Molecular Weight: 147.13
Synonyms: 1-Aminopropane-1,3-dicarboxylic acid;2-Aminopentanedioic acid;2-Aminopentanedioic acid, (S)-;AI3-18472;Acide glutamique;Acido glutamico;Acidum glutamicum;Acidum glutaminicum;Aciglut;CCRIS 7314;D-Glutamiensuur;EPA Pesticide Chemical Code 374350;FEMA No. 3285;Glusate;Glutacid;Glutamate, L-;Glutamic acid (H-3);Glutamic acid (VAN);Glutamic acid, (S)-;Glutamicol;Glutamidex;Glutaminic acid;Glutaminic acid (VAN);Glutaminol;Glutaton;L-2-Aminoglutaric acid;L-Glutaminic acid;NSC 143503;Pentanedioic acid, 2-amino-, (S)-;UNII-3KX376GY7L;alpha-Aminoglutaric acid;alpha-Aminoglutaric acid (VAN);
EINECS: 200-293-7
Density: 1.41 g/cm3
Melting Point: 205 °C (dec.)(lit.)
Boiling Point: 333.783 °C at 760 mmHg
Flash Point: 155.667 °C
Solubility: 7.5 g/L (20 °C) in water
Appearance: White cryst. powder
Hazard Symbols: IrritantXi
Risk Codes: 36/37/38
Safety: 24/25-36-26
Transport Information:
PSA: 100.62000
LogP: -0.03660
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    Name Glutamic acid Molecular Formula C4H7NO4 Molecular Weight 133.103 CAS Registry Number 56-84-8 density

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Specification

1. Introduction of L-Glutamic acid

L-Glutamic acid, with the IUPAC Name of (2S)-2-Aminopentanedioic acid, is one kind of white cryst. powder. This chemical belongs to the Product Categories which include Food & Feed ADDITIVES; chiral; Glutamic acid [Glu, E]; Amino Acids and Derivatives; alpha-Amino Acids; Amino Acids; Biochemistry; for Resolution of Bases; Optical Resolution; Synthetic Organic Chemistry; Nutritional Supplements; Amino Acids; Chiral Compound; Glutamate receptor; Glutamate; fine chemicals; glutamic acid; amino acid; bio-chemical; chemicals; food additive; food additives; nutritional supplement; organic acids; pharmaceutical intermediate.

2. Properties of L-Glutamic acid

L-Glutamic acid has the following property datas: (1)Melting point: 205 °C; (2)Index of Refraction: 1.522; (3)Molar Refractivity: 31.83 cm3; (4)Molar Volume: 104.3 cm3; (5)Surface Tension: 69.2 dyne/cm; (6)Density: 1.409 g/cm3; (7)Flash Point: 155.7 °C; (8)Enthalpy of Vaporization: 63.39 kJ/mol; (9)Boiling Point: 333.8 °C at 760 mmHg; (10)Vapour Pressure: 2.55E-05 mmHg at 25 °C; (11)storage temp.: Store at RT.; (12)solubility: 1 M HCl: 100 mg/mL; (13)Water Solubility: 7.5 g/L (20 °C).

3. Structure Descriptors of L-Glutamic acid

You could convert the following datas into the molecular structure:
InChI: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1 
InChIKey: InChIKey=WHUUTDBJXJRKMK-VKHMYHEASA-N 
Smiles: [C@H](CCC(=O)O)(C(=O)O)N

4. Toxicity of L-Glutamic acid

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo intravenous 117mg/kg (117mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING American Journal of the Medical Sciences. Vol. 214, Pg. 281, 1947.
human TDLo oral 71mg/kg (71mg/kg) BEHAVIORAL: HEADACHE Science. Vol. 163, Pg. 826, 1969.
 
rabbit LD50 oral > 2300mg/kg (2300mg/kg)   FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 42, 1970.
rat LD50 oral > 30gm/kg (30000mg/kg)   FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 42, 1970.

5. Safety Information of L-Glutamic acid
Hazard Codes of L-Glutamic acid (CAS NO.56-86-0): IrritantXi
Risk Statements: 36/37/38 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26 
S24/25: Avoid contact with skin and eyes. 
S36: Wear suitable protective clothing. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: LZ9700000
F: 10
Human systemic effects by ingestion and intravenous routes: headache and nausea or vomiting. When heated to decomposition it emits toxic fumes of NOx.

6. Production of L-Glutamic acid

L-Glutamic acid can be obtained directly from fermentation of carbohydrates with Micrococcus glutarnicus or Brevihacterium divaricatum.

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