FLUORINATION OF AROMATIC α-HYDROXYESTERS WITH N,N-DIETHYL-1,1,2,3,3,3-HEXAFLUOROPROPANEAMINE

Article abstract of DOI:10.1016/S0022-1139(00)82371-4

The reaction of N,N-diethyl-1,1,2,3,3,3-hexafluoropropaneamine (PPDA) with aromatic α-hydroxyesters exchanged F for OH and gave their corresponding fluorides.For example, ethyl 2-fluoro-2-(p-tolyl) acetate was obtained from the reaction of ethyl 2-hydroxy-2-(p-tolyl) actate with PPDA.