Enantioselective Total Syntheses of Indolizidine Alkaloids 167B and 209D

DOI: 10.1021/jo00302a038

Source and publish data:

Journal of Organic Chemistry p. 4688 - 4693 (1990)

Update date:2022-08-05

Topics:

Authors:

Polniaszek, Richard P.

Belmont, Stephen E.

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Article abstract of DOI:10.1021/jo00302a038

Enantioselective total syntheses of the indolizidine alkaloids 167B and 209D are described.The sytheses proceed via a common late-stage intermediate, amino nitrile 8.Each alkaloid was prepared in 10 steps and approximately 23percent overall yield from (S)

Full text of DOI:10.1021/jo00302a038

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