Synthesis of steroidal pyrimidines

Article abstract of DOI:10.1080/00397919608003757

Selected aryl aldehydes were treated with 17-oxo-5-androsten-3β-yl acetate (I) to give the corresponding 16-arylidene 17-oxo-5-androsten-3β-yl acetates (IIa-e). Condensation of these chalcones with urea revealed the formation of the corresponding substituted pyrimidin-2'-ones (IIIa-e) respectively.

Full text of DOI:10.1080/00397919608003757

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Synthetic Communications: An
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Synthesis of Steroidal
Pyrimidines
Keshava R. Rapole a b , A. H. Siddiqui c , B. Dayal
a b , A. K. Batta a b , S. J. Rao d , P. Kumar a b & G.
Salen a b
a Department of Medicine , University of Medicine
& Dentistry of New Jersey, New Jersey Medical
School , Newark, NJ, 07103
b VA Medical Center , East Orange, NJ, 07019
c Department of Chemistry , Nizam College,
Osmania University , Hyderabad, India , 500001
d Department of Chemistry , Drexel University ,
Philadelphia, Pennsylvania, 19104
Published online: 21 Aug 2006.
To cite this article: Keshava R. Rapole , A. H. Siddiqui , B. Dayal , A. K. Batta , S.
J. Rao , P. Kumar & G. Salen (1996) Synthesis of Steroidal Pyrimidines, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 26:18, 3511-3515, DOI: 10.1080/00397919608003757
To link to this article: http://dx.doi.org/10.1080/00397919608003757
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