[3 + 3]-Carbocyclizations of nitroallylic esters and enamines with stereoselective formation of up to six new stereogenic centers

DOI: 10.1021/ja00177a026

Source and publish data:

Journal of the American Chemical Society p. 7625 - 7638 (1990)

Update date:2022-08-04

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Authors:

Seebach, Dieter

Missbach, Martin

Calderari, Giorgio

Eberle, Martin

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Article abstract of DOI:10.1021/ja00177a026

Enamines (1) from open-chain and cyclic ketones react with 2-nitro-2-propen-l-yl acetates and pivalates (nitroallylic esters 2) to give, after aqueous workup, 4-nitrocyclohexanones (Schemes I-IV; products 3-18). Monocyclic as well as bicyclic [4.3.1], [3.

Full text of DOI:10.1021/ja00177a026

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