Amino ketone and amino alcohol derivatives of benzoxazolinone: synthesis, adrenergic and antihypertensive properties

Article abstract of DOI:10.1016/0223-5234(90)90120-R

The concept of bioisosterism between benzoxazolinone and pyrocatechol has led to the synthesis of benzoxazolinone analogues of the catecholamines which display β- and α-blocking properties.In this paper, we report the synthesis of analogues in which the a