USE OF POTASSIUM FLUORIDE IN THE CYCLIZATION OF 3-HETERO-1,5-DIALDEHYDES WITH NITROMETHANE AND ETHYL NITROACETATE

Article abstract of DOI:10.1016/S0040-4020(01)90542-3

The use of potassium fluoride as catalyst in the cyclization reactions of dialdehydes is described for the first time.This compound is an efficient catalyst in the cyclizations with nitromethane and ethyl nitroacetate.The yields obtained are similar or higher than those reported when other catalysts are used and the stereoselectivity was major when the dialdehyde prepared by periodate oxidation of methyl α-L-rhamnopyranoside was used.