Synthesis of 3-Alkoxyalkanoic Esters from Acetals. A Novel Application of Reformatsky Reagents in Asymmetric Synthesis

DOI: 10.1055/s-1990-26859

Source and publish data:

Synthesis p. 305 - 311 (1990)

Update date:2022-08-04

Topics:

Authors:

Basile, Tiziana

Tagliavini, Emilio

Trombini, Claudio

Umani-Ronchi, Achille

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Article abstract of DOI:10.1055/s-1990-26859

3-Alkoxyalkanoic esters are directly obtained in high yield from the reaction of acetals with Reformatsky reagents in the presence of titanium(IV)chloride or diethyl ether-boron trifluoride complex in dichloromethane.The reaction of ethyl 4-bromo-2-buteno

Full text of DOI:10.1055/s-1990-26859

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