Antineoplastic Activity of Didemnin Congeners: Nordidemnin and Modified Chain Analogues

DOI: 10.1021/jm00106a002

Source and publish data:

Journal of Medicinal Chemistry p. 486 - 491 (1991)

Update date:2022-08-04

Topics:

Authors:

Jouin, Patrick

Poncet, Joel

Dufour, Marie-Noelle

Aumelas, Andre

Pantaloni, Antoine

et al. et al.

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Article abstract of DOI:10.1021/jm00106a002

Nordidemnin (2), a natural analogue of the marine cyclodepsipeptide didemnin B (1b), showed cytotoxic activity against L1210 leukemia and antineoplastic activity against P388 leukemia as well as B16 melanoma; nordidemnin (2) was as active as didemnin B (1

Full text of DOI:10.1021/jm00106a002

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