CANNABISIN A, AN ARYLNAPHTHALENE LIGNANAMIDE FROM FRUITS OF CANNABIS SATIVA

Article abstract of DOI:10.1016/S0031-9422(00)98242-6

A new lignanamide, named cannabisin A, a known lignanamide, grossamide, and three known amides, N-trans-caffeoyltyramine, N-trans-feruloyltyramine, N-p-coumaroyltyramine, were isolated from the fruits of Cannabis sativa.The structure of cannabisin A has been established as 6,7-dihydroxy-1-(3,4-dihydroxyphenyl)-N¹,N²-bis-<2-(4-hydroxyphenyl)ethyl>-2,3-naphthalenedicarboxamide, on the basis of chemical and spectral evidence.Key Word Index - Cannabis sativa; Cannabidaceae; fruits; cannabisin A; grossamide; N-trans-caffeoyltyramine; N-trans-feruloyltyramine; N-p-coumaroyltyramine.