A HIGHLY EFFICIENT METHOD FOR THE PREPARATION OF 2-ARYL SUBSTITUTED CARBAPENEMS EXPLOITING A Pd(0) MEDIATED CROSS-COUPLING REACTION

DOI: 10.1016/0040-4039(90)80165-I

Source and publish data:

Tetrahedron Letters p. 2853 - 2856 (1990)

Update date:2022-07-30

Topics:

Authors:

Rano, Thomas A.

Greenlee, Mark L.

DiNinno, Frank P.

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Article abstract of DOI:10.1016/0040-4039(90)80165-I

A remarkable mild procedure for the synthesis of 2-aryl substituted carbapenems via a palladium catalyzed coupling reaction of a vinyl triflate with aryl stannanes is described.Employing Pd2(DBA)3*CHCl3 as the catalyst and tris(2,4,6-trimethoxyphenyl)phos

Full text of DOI:10.1016/0040-4039(90)80165-I

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