Manganese(III)-promoted tandem oxidation and cyclization of β-keto ester derivatives of terpenoids

Article abstract of DOI:10.1002/adsc.201100215

A new type of terpenoid cyclization directed by a β-keto ester moiety has been developed, which proceeded by manganese(III)-initiated oxidation of the β-keto ester, followed by an intramolecular hetero Diels-Alder reaction with the terpenoid chain. This reaction produces polycyclic dihydropyrans in high yields and stereoselectivities under mild conditions. Copyright