Journal of the American Chemical Society p. 183 - 196 (1991)
Update date:2022-08-05
Topics: Synthesis Structure Experiment Molecular tweezers Active site functionality
Zimmerman, Steven C.
Zeng, Zijian
Wu, Weiming
Reichert, David E.
A series of molecules has been synthesized in which a functional group is buried inside an aromatic binding cleft. These novel compounds, called "molecular tweezers", have a methyl ester (6a, 7-9a, 10a), a carboxylic acid (6b, 9b, 10b, 45), or a nitrile (
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