
Tetrahedron Letters p. 2554 - 2556 (2011)
Update date:2022-08-04
Topics:
Denton, Ross M.
Scragg, James T.
Saska, Jan
A concise and protecting group free synthesis of the naturally occurring neolignan 4′-O-methyl honokiol is developed. The key biaryl bond is constructed by 1,2-addition of an aryl Grignard reagent to a dienone followed by rearrangement.
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