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A green expedient synthesis of pyridopyrimidine-2-thiones and their antitubercular activity

DOI: 10.1016/j.bmcl.2011.03.045

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Bioorganic and Medicinal Chemistry Letters p. 3012 - 3016 (2011)

Update date:2022-08-05

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Authors:

Rajesh, Stephen MichaelRajesh, Stephen Michael

Kumar, Raju SureshKumar, Raju Suresh

Libertsen, Lawzer ArunLibertsen, Lawzer Arun

Perumal, SubbuPerumal, Subbu

Yogeeswari, PerumalYogeeswari, Perumal

Sriram, DharmarajanSriram, Dharmarajan

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Article abstract of DOI:10.1016/j.bmcl.2011.03.045

The pseudo four-component domino reactions of N-substituted-4-piperidones, substituted aromatic aldehydes and thiourea in the presence of solid sodium ethoxide under solvent-free conditions afforded pyridopyrimidine-2-thiones in almost quantitative yields

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Full text of DOI:10.1016/j.bmcl.2011.03.045

Products guided by the article

Product name:(E)-6-benzyl-8-(2,4-dichlorobenzylidene)-4-(2,4-dichlorophenyl)-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidine-2(1H)-thione

Cas No:1310325-89-3

1310325-89-3

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