Journal of Organic Chemistry p. 751 - 762 (1991)
Update date:2022-09-26
Topics:
Mathre, David J.
Jones, Todd K.
Xavier, Lyndon C.
Blacklock, Thomas J.
Reamer, Robert A.
et al.
A practical two-step enantioselective synthesis of α,α-diaryl-2-pyrrolidinemethanols (1) from proline, based on the addition of aryl Grignard reagents to proline-N-carboxanhydride (3), is reported.An investigation into the chemistry of the corresponding B-alkyl- and B-aryloxazaborolidines (2) led to the development of a reliable procedure for their preparation.
View MoreContact:86-379-63338609
Address:Jiudian Village,Deting Town,Song County,Luoyang
Puyang Huicheng Electronic Material Co., Ltd
website:http://huichengchem.weba.testwebsite.cn/index_en.html
Contact:+86-393-8910800
Address:West Section Shengli Road, Puyang457000, China
Hefei EnliPharma Tecnology Co.,Ltd
Contact:0086-551-66399836
Address:Qing Cheng ShuiXiang Building 805, Mengcheng North Road , ShuangFeng Economic Development Zone Anhui HeFei
Contact:+86-13914766747
Address:Floors 21&22, Jin Cheng Tower, No. 216 Middle Longpan Road, Nanjing
lianyungang jinkang pharmaceutical technology co., ltd.
Contact:008651885445517
Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
Doi:10.1039/c1cc11005e
(2011)Doi:10.1080/15533174.2013.819904
(2015)Doi:10.1002/anie.201507363
(2015)Doi:10.1016/j.bmcl.2011.04.141
(2011)Doi:10.1021/jm5007534
(2014)Doi:10.1016/j.cclet.2011.07.020
(2011)
