332
M. Xu et al. / Inorganica Chimica Acta 384 (2012) 324–332
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Two new water-soluble Ln(I) complexes of acylhydrazone
ligand derived from ofloxacin were synthesized and characterized.
The DNA binding mode of Ln(III) complexes and ligand with CT
DNA were studied via spectra, CV and viscosity measurement.
The experiment results suggest that ligand and its Ln(III) com-
plexes bind to DNA via intercalation mode, and Ln(I) complexes
have higher binding ability than free ligand. We also find that both
Ln(III) complexes can effectively cleave plasmid DNA without addi-
tion of external agents. DNA cleavage mechanism studies show
that the Ln(III) complexes examined here may be capable of pro-
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Moreover, Ln(I) complexes have better antioxidant activity than
pure ligand.
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Thanks Henan Province Science and Technology Key Project
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Appendix A. Supplementary material
CCDC 768805 and 768806 contain the supplementary crystallo-
graphic data for complexes Pr(III) and Nd(III). These data can be ob-
tained free of charge from The Cambridge Crystallographic Data
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