A 3-D model for 5-HT(1A)-receptor agonists based on stereoselective methyl-substituted and conformationally restricted analogues of 8-hydroxy-2-(dipropylamino)tetralin

DOI: 10.1021/jm00106a004

Source and publish data:

Journal of Medicinal Chemistry p. 497 - 510 (1991)

Update date:2022-08-05

Topics: Stereoselective Analogues Agonists Experimental Conformationally restricted

Authors:

Mellin Mellin

Vallgarda

Nelson Nelson

Bjork Bjork

Anden Anden

Csoregh Csoregh

Arvidsson

Hacksell

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Article abstract of DOI:10.1021/jm00106a004

The enantiomers of cis- and trans-1,2,3,4,4a,5,10,10a-octahydro-9-hydroxy-1-propylbenzo[g] quinolines (10 and 11, respectively) and the enantiomers of trans-1,2,3,4,4a,5,6,10b-octahydro-10-hydroxy-4-propylbenzo[f] quinoline (12) have been synthesized and

Full text of DOI:10.1021/jm00106a004

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