Steroids p. 263 - 265 (1990)
Update date:2022-08-05
Topics:
Li, Tong-Shuang
Li, Yu-Lin
Liang, Xiao-Tian
5α-(17R,20R)-14,15-Secocholestane (12) was synthesized from cholesterol (1) in 12 steps.The key intermediate, 5α-cholest-14-en-3β-yl acetate (4), underwent ozonization, reduction, hydrolysis, and oxidation to provide 5α-14,15-secocholesta-3,14,15-trione (8).One of the Clemmensen reduction products of 8 is 5α(17R,20R)-14,15-secocholest-15-ol (II), treatment of the alcohol (II) with tosyl chloride and subsequent reduction with lithium aluminum hydride yielded the target molecule (12).
View MoreContact:+86 21 5017 5386
Address:No 999,Jiangyue Rd, Minhang Dist ,201114,Shanghai ,China
Hangzhou Taiyan Trading Co., Ltd(expird)
Contact:+86-13777583958
Address:NO.63, Xingyi Street, Xihu District, Hangzhou, Zhejiang, China
website:http://www.angchenchem.com
Contact:+86-510-88302099 82327577
Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China
Yantai Derun Liquid Crystal Materials Co. Ltd.
website:http://www.ytderun.com
Contact:86-535-6300169
Address:ROOM 90, XIANGFU STREET, FUSHAN NEW-HIGH-TECH IDUSTRY ZONE, YANTAI
website:http://www.apeptides.com/en/
Contact:+86-21-60871011
Address:No. 80 Chuanshan Shuyuan Steet,Pudong,Shanghai
Doi:10.1016/0031-9422(90)85387-U
(1990)Doi:10.1002/chem.201502418
(2015)Doi:10.1002/jps.2600520918
(1963)Doi:10.1016/j.molstruc.2011.06.006
(2011)Doi:10.1016/S0040-4039(00)97997-8
(1990)Doi:10.1002/hlca.19870700508
(1987)
