Hexacyclic Indole Alkaloids. A Highly Convergent Total Synthesis of Cuazine

DOI: 10.1021/jo00007a024

Source and publish data:

Journal of Organic Chemistry p. 2380 - 2386 (1991)

Update date:2022-08-05

Topics:

Authors:

Palmisano, Giovanni

Danieli, Bruno

Lesma, Giordano

Passarella, Daniele

Toma, Lucio

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Article abstract of DOI:10.1021/jo00007a024

A novel route to the hexacyclic indole alkaloid cuanzine 1 has been developed.Key synthetic steps include the cyclocondensation of the imine 8 with the dihydrofuran 10 followed by homogeneous-catalyzed hydrogenation, wherein the COOMe group at C(20) serve

Full text of DOI:10.1021/jo00007a024

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