Helvetica Chimica Acta p. 1260 - 1268 (2011)
Update date:2022-08-03
Topics:
Majzlik, Petr
Omelka, Ladislav
Superatova, Renata
Holubcova, Petra
A series of substituted 4-methylphenols 1 and 2 was oxidized with PbO 2 in the presence of nitroso compounds 3-10. The formation of adducts of benzyl radicals with the nitroso spin traps in the reaction mixture was established, suggesting the abstraction of an H-atom from the methyl substituent of 1 or 2. In the consecutive steps, the adducts underwent a further rearrangement to the corresponding nitrones. When the starting phenol contained bulky tBu groups in ortho-position (see 2,6-di(tert-butyl)-4- methylphenol (1a)), the stable 2,6-di(tert-butyl)-4R-phenoxy radicals (R=-CH=N+(O-)-X) were detected as the final radical products. The indirect evidence of nitrones in the reaction mixture was performed in one case by the reaction with a RO2 radicals. Copyright
View MoreShandong Bolode Bio-Technology Co., LTD
Contact:+86-0531-58966870
Address:136 Jingyi Road,Huaiyin District,Jinan,Shandong,China
Suzhou Howsine Biological Technology Co.,Ltd(expird)
website:http://www.howsine.com
Contact:86-512-67262751
Address:No 3,Weihua Road ,Suzhou Industrial Park ,Jiangsu ,China.
Wuhan Jadechem International Trade Co.,Ltd.
website:http://www.jadechem-intl.com
Contact:+86-27-83527060
Address:Room 502,Building C11,Software new city No.8,Huacheng Avenue,East Lake High-tech development zone,Wuhan,Hubei,China
Nanjing lanbai chemical Co.,Ltd.
Contact:+86-25-85499326
Address:Room 908, 9F Taiyue Building,No.285 Heyan Road
Contact:+86-22-26358246
Address:601-4-20, Fujiayuan, Tiantai Road, Hebei District, Tianjin, China
Doi:10.1016/j.bioorg.2020.103735
(2020)Doi:10.1039/c1jm10817d
(2011)Doi:10.1002/ejoc.201100231
(2011)Doi:10.1016/S0040-4039(00)97984-X
(1990)Doi:10.1002/anie.201102092
(2011)Doi:10.1016/j.dyepig.2013.12.020
(2014)