An efficient synthetic pathway to the macroline-type indole alkaloids, talcarpine and alstonerine from ajmaline

DOI: 10.1016/S0040-4020(01)86414-0

Source and publish data:

Tetrahedron p. 1383 - 1392 (1991)

Update date:2022-08-04

Topics:

Authors:

Takayama, Hiromitsu

Phisalaphong, Chada

Kitajima, Mariko

Aimi, Norio

Sakai, Shin-Ichiro

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Article abstract of DOI:10.1016/S0040-4020(01)86414-0

Ajmaline (6) was transformed into two macroline-related indole alkaloids, talcarpine (1) and alstonerine (2) via the common synthetic intermediate (13). The stereochemistry at C19 position in talcarpine (1) and talpinine (5) were elucidated by NOE experim

Full text of DOI:10.1016/S0040-4020(01)86414-0

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