Regioselective addition of nbutyllithium on secondary cinnamyl amides: 'Michael' versus 'contra-Michael' process

DOI: 10.1016/S0040-4039(99)00494-3

Source and publish data:

Tetrahedron Letters p. 3379 - 3382 (1999)

Update date:2022-07-29

Topics:

Authors:

Bremand, Nathalie

Marek, Ilan

Normant, Jean F.

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Article abstract of DOI:10.1016/S0040-4039(99)00494-3

Lithiated secondary cinnamyl amides undergo a preferred 'contra-Michael' addition of nbutyllithium, complexed with (-)sparteine, in a non polar solvent.

Full text of DOI:10.1016/S0040-4039(99)00494-3

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